High Altitude Long Endurance (HALE in short ) UAV has made great development since its birth and participation in war. With the expansion of combat mission to high-risk confrontation battlefield, HALE fly-wing UAV has become a hotspot in the world today. In this paper,the requirements of HALE fly-wing UAV for turbofan engine are described, effect of key design parameters on the performance of turban engine is analyzed based on the basic principle of aero engine, the key problems and research progress of HALE fly-wing UAV are summarized. This paper has important reference value of the selection of turbofan engine for HALE fly-wing UAV and the improvement of its adaptability design.