The state-of-art of Five Qualities (Reliability, Maintainability, Testability, Safety and Supportability) home and abroad is compared, and the Five Qualities Integration design characteristics and engineering application problems such as data, activities and tools integration etc are summarized. On the basis of that, Five Qualities Integration design program and design requirements during aircraft development is studied. Five Qualities integration environment is Preliminary built, including environment building rules, environment schedule and the required key techniques, all of which are described in detail.