There is eccentric error between the geometric center of the gear blank and the axis of the rotary table during the aero gear grinding process. The machining precision of grinding tooth accuracy is reduced. In order to improve the precision of gear grinding, according to the working principle of CNC grinding wheel grinding machine, the eccentric error of the installation is proportional to the deviation from the single pitch and the total cumulative deviation of the tooth distance by analysis. The compensation method of installation eccentricity error is put forward. The mathematical model of offset error compensation is established. The feed compensation increment of the grinding wheel in the two directions of X and Y is obtained through the mathematical model. Taking the YK73125 CNC grinding wheel grinding machine as an example, the eccentric error compensation experiment is carried out. The single pitch limit deviation is reduced by 0.9 and 1.6 on left and right tooth surfaces. The total cumulative pitch error is reduced by 49.6 and 43.3 on left and right tooth surfaces. The experimental results show that the installation eccentricity error compensation for gear grinding can effectively reduce the total deviation of the single pitch deviation and the cumulative tooth distance.