Aiming at Daxing Airport and Tianfu International Airport’s cross-runway, approaching aircraft may have a missed approach in one landing mode, which will affect the safety of take-off and departure aircraft on another runway, and affect the different distances from the approaching aircraft to the end of the runway. The timing of aircraft release was studied. First, calculate the distance from the approaching and go-around aircraft to the end of the runway by establishing a collision risk model; then establish the wake interval model between the cross-runway approach and go-around and take-off and departure aircraft, and calculate the tail generated by the take-off and departure aircraft Whether the flow affects the go-around aircraft to determine the wake safety distance, and finally compare the safety interval calculated by the collision risk model with the safety interval calculated by the wake model, whichever is greater, is the final safety of the approaching aircraft from the end of the runway distance. The controllers of Daxing Airport and Tianfu International Airport can determine the time to release aircraft for take-off based on the safety interval to ensure the safety of aircraft entering and leaving the field.