As the development of aircraft demand recently years，new material and new craft are emerging, the test and validation technology of aircraft will also face new challenges. As the key measures of networking and intelligentization, 5G technology will promote the innovation and reform of strength test technology effectively. First, the present situation and development trend of structural strength test technology for full-scale aircraft was introduced briefly, and one new idea of structure strength test for full-scale aircraft based on 5G was proposed through the research of the demand of full-scale aircraft strength test. Second, the incidence matrix of test and 5G technology was formulated through the analysis of advantages and features of 5G for strength test of aircraft，the typical test scenarios based on 5G were planned. Finally, the development and application of inspection and monitor system based on 5G was carried out for fatigue test of one type of aircraft successfully, the results show that the intelligent facilities based on 5G technology will improve the level of test significantly and have significant implication for intelligentization of test.