With the increasing use of software tools in the process of developing and verifying airborne software to meet DO-178C, In order to ensure its airworthiness and safety, DO-178C uses DO-330 as a guide for software tool qualification process. At present, COTS tools can not meet the requirements of specific project development and verification. The evaluation tool qualification level, life cycle process and objective of tool qualification in DO-330 are used as the guidance basis. The main concerns and difficulties in the process of DO-330 engineering practice are analysed. Combined with the actual project, the qualification process of self-developed tool to meet the requirements of DO-330 is given. The research results show that the self-developed tool qualification of Tool Qualification Level 5 (TQL-5) proposed in this paper has engineering feasibility and has made substantial progress. It provides reference and guidance for organizations that cannot use COTS to meet specific project requirements and need to perform software tool qualification according to DO-330 requirements.